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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EPB41L5
All Species:
20
Human Site:
T596
Identified Species:
33.85
UniProt:
Q9HCM4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9HCM4
NP_065960.2
733
81856
T596
A
N
V
Q
D
A
A
T
N
S
A
V
L
N
E
Chimpanzee
Pan troglodytes
XP_001157953
733
81845
T596
A
S
V
Q
D
A
A
T
N
S
A
V
L
N
E
Rhesus Macaque
Macaca mulatta
XP_001088764
726
81122
T590
A
N
V
Q
D
A
A
T
N
S
A
M
L
N
E
Dog
Lupus familis
XP_532028
914
101864
V684
S
S
L
Q
D
A
N
V
R
S
P
I
P
I
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGS1
731
81617
T595
A
S
V
Q
D
A
A
T
N
S
T
A
F
N
E
Rat
Rattus norvegicus
Q5FVG2
731
81700
T595
A
S
V
Q
D
A
A
T
N
S
T
V
F
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509941
820
90648
S596
H
N
P
E
G
L
L
S
F
S
E
A
S
N
E
Chicken
Gallus gallus
XP_422083
502
57358
E368
A
R
R
S
A
S
F
E
R
R
P
S
K
R
Y
Frog
Xenopus laevis
NP_001080234
498
57093
S364
K
S
S
K
P
R
R
S
S
S
F
E
R
R
P
Zebra Danio
Brachydanio rerio
O57457
619
70690
R485
S
E
S
E
N
S
N
R
E
H
R
K
K
R
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650291
972
105216
A773
G
N
G
P
Y
S
N
A
T
F
V
S
G
F
S
Honey Bee
Apis mellifera
XP_623974
809
90976
Q675
L
N
P
K
I
S
N
Q
S
Q
N
P
F
N
P
Nematode Worm
Caenorhab. elegans
P28191
1026
115075
Q797
D
D
T
R
V
T
L
Q
A
S
P
S
G
D
Y
Sea Urchin
Strong. purpuratus
XP_788387
843
92835
D598
L
Q
T
P
Q
N
L
D
M
D
F
D
E
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
95.2
39.8
N.A.
83.9
83.6
N.A.
56.5
56.6
54.4
28.5
N.A.
36.8
38.9
24.3
39.1
Protein Similarity:
100
99.3
96.3
52.1
N.A.
89.2
88.4
N.A.
65.1
62.2
60.9
44.7
N.A.
51.8
53.1
40.1
56.7
P-Site Identity:
100
93.3
93.3
26.6
N.A.
73.3
80
N.A.
26.6
6.6
6.6
0
N.A.
6.6
13.3
6.6
0
P-Site Similarity:
100
100
100
53.3
N.A.
80
86.6
N.A.
40
13.3
33.3
26.6
N.A.
13.3
33.3
26.6
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
43
0
0
0
8
43
36
8
8
0
22
15
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
0
0
43
0
0
8
0
8
0
8
0
8
0
% D
% Glu:
0
8
0
15
0
0
0
8
8
0
8
8
8
8
43
% E
% Phe:
0
0
0
0
0
0
8
0
8
8
15
0
22
8
0
% F
% Gly:
8
0
8
0
8
0
0
0
0
0
0
0
15
0
8
% G
% His:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
8
0
8
0
% I
% Lys:
8
0
0
15
0
0
0
0
0
0
0
8
15
0
0
% K
% Leu:
15
0
8
0
0
8
22
0
0
0
0
0
22
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
8
0
0
0
% M
% Asn:
0
36
0
0
8
8
29
0
36
0
8
0
0
50
8
% N
% Pro:
0
0
15
15
8
0
0
0
0
0
22
8
8
0
15
% P
% Gln:
0
8
0
43
8
0
0
15
0
8
0
0
0
0
0
% Q
% Arg:
0
8
8
8
0
8
8
8
15
8
8
0
8
22
8
% R
% Ser:
15
36
15
8
0
29
0
15
15
65
0
22
8
0
8
% S
% Thr:
0
0
15
0
0
8
0
36
8
0
15
0
0
0
0
% T
% Val:
0
0
36
0
8
0
0
8
0
0
8
22
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _